Professor Michael Sacks is the W. A. “Tex” Moncrief, Jr. Simulation-Based Engineering Science Chair and a world authority on cardiovascular biomechanics. His research focuses on the quantification and modeling of the structure-mechanical properties of native and engineered cardiovascular soft tissues. He is a leading international authority on the mechanical behavior and function of the native and replacement heart valves. He is also active in the biomechanics of engineered tissues, and in understanding the in-vitro and in-vivo remodeling processes from a functional biomechanical perspective. Dr. Sacks is currently director of the ICES Center for Cardiovascular Simulation and Professor of Biomedical Engineering.
His research includes multi-scale studies of cell/tissue/organ mechanical interactions in heart valves and is particularly interested in determining the local stress environment for heart valve interstitial cells. Recent research has included developing novel multi-scale models of the mitral valve and bioprosthetic heart valves, as well as constitutive models of ventricular myocardium that allow for the separation of the individual contributions of the myocyte and connective tissue networks.